 |
| Image: tenebrousmagazine.blogspot.com |
Indeed, research has shown that compounds in plants have pharmacokinetic effects. [3] Dandelion, long speculated to have antioxidant activity and hepatoprotective properties, is one such plant
Powerful Antioxidant, Resistant to Swelling
Dandelion contains chemicals whose biological activities are actively being explored for roles in human health. In particular, evidence suggests that dandelion contains antioxidant and redness-resistant compounds. [4] [5]
One study investigated the antioxidative effects of dandelion root in rabbits fed a high-cholesterol diet. Results showed that dandelion positively affected antioxidant enzyme activities and lipid profiles. Researchers believe this suggests dandelion could protect against oxidative stress related to certain circulatory disorders. [6]
Effect of Dandelion Root on the Digestive System and Gallbladder
The Institute of Agricultural Medicine in Poland tested therapeutic herbs for kynurenic acid, an amino acid that has generated interest for digestive system support, specifically bile production. The highest concentration of this compound was detected in dandelion. [7] Because dandelion helps to stimulate bile production and bile transport toxins out of the body, dandelion root may support your body’s natural immune response. A study devised to compare the activity of artichoke, dandelion, turmeric and rosemary found their antioxidant activity to support the rationale the traditional inclusion of these ingredients in gallbladder applications. [8]
Relation to the Liver
Acetaminophen toxicity causes oxidative stress in the liver. Could natural antioxidant compounds counteract it? A study designed to answer that question found that dandelion extract demonstrated antioxidant activity against free radicals to counteract acetaminophen liver toxicity. [9] Animal studies have been successful in finding beneficial links between certain liver problems and dandelion. [10] [11]
- Dr. Edward F. Group III, DC, ND, DACBN, DCBCN, DABFM
Source: globalhealingcenter.com
References:
Schütz K, Carle R, Schieber A. Taraxacum–a review on its phytochemical and pharmacological profile. J Ethnopharmacol. 2006 Oct 11;107(3):313-23. Epub 2006 Jul 22. Review.
Lee BR, Lee JH, An HJ. Effects of Taraxacum officinale on fatigue and immunological parameters in mice. Molecules. 2012 Nov 7;17(11):13253-65. doi: 10.3390/molecules171113253.
Rodriguez-Fragoso L, Reyes-Esparza J, Burchiel SW, Herrera-Ruiz D, Torres E. Risks and benefits of commonly used herbal medicines in Mexico. Toxicol Appl Pharmacol. 2008 Feb 15;227(1):125-35. Epub 2007 Oct 12. Review.
González-Castejón M, Visioli F, Rodriguez-Casado A. Diverse biological activities of dandelion. Nutr Rev. 2012 Sep;70(9):534-47. doi: 10.1111/j.1753-4887.2012.00509.x. Epub 2012 Aug 17. Review.
Jeon HJ, Kang HJ, Jung HJ, Kang YS, Lim CJ, Kim YM, Park EH. Anti-inflammatory activity of Taraxacum officinale. J Ethnopharmacol. 2008 Jan 4;115(1):82-8. Epub 2007 Sep 15.
Choi UK, Lee OH, Yim JH, Cho CW, Rhee YK, Lim SI, Kim YC. Hypolipidemic and antioxidant effects of dandelion (Taraxacum officinale) root and leaf on cholesterol-fed rabbits. Int J Mol Sci. 2010 Jan 6;11(1):67-78. doi: 10.3390/ijms11010067.
Urski MP, Turska M, Zgrajka W, Bartnik M, Kocki T, Turski WA. Distribution, synthesis, and absorption of kynurenic acid in plants. Planta Med. 2011 May;77(8):858-64. doi: 10.1055/s-0030-1250604. Epub 2010 Dec 14.
Menghini L, Genovese S, Epifano F, Tirillini B, Ferrante C, Leporini L. Antiproliferative, protective and antioxidant effects of artichoke, dandelion, turmeric and rosemary extracts and their formulation. Int J Immunopathol Pharmacol. 2010 Apr-Jun;23(2):601-10.
Colle D, Arantes LP, Gubert P, da Luz SC, Athayde ML, Teixeira Rocha JB, Soares FA. Antioxidant properties of Taraxacum officinale leaf extract are involved in the protective effect against hepatoxicity induced by acetaminophen in mice. J Med Food. 2012 Jun;15(6):549-56. doi: 10.1089/jmf.2011.0282.
Domitrović R, Jakovac H, Romić Z, Rahelić D, Tadić Z. Antifibrotic activity of Taraxacum officinale root in carbon tetrachloride-induced liver damage in mice. J Ethnopharmacol. 2010 Aug 9;130(3):569-77. doi: 10.1016/j.jep.2010.05.046. Epub 2010 Jun 2.
You Y, Yoo S, Yoon HG, Park J, Lee YH, Kim S, Oh KT, Lee J, Cho HY, Jun W. In vitro and in vivo hepatoprotective effects of the aqueous extract from Taraxacum officinale (dandelion) root against alcohol-induced oxidative stress. Food Chem Toxicol. 2010 Jun;48(6):1632-7. doi: 10.1016/j.fct.2010.03.037. Epub 2010 Mar 27.
