Tylenol can kill you; new warning admits it can cause liver damage and death

It has been a common household name in over-the-counter pain relief for more than 50 years. But the popular painkiller drug Tylenol is getting a major labeling makeover following a string of personal injury lawsuits. According to the Associated Press (AP), so many Tylenol users these days are suffering major liver damage or dying that the drug's manufacturer, McNeil Consumer Healthcare, has decided to put a large, red warning label on the cap that informs users about the drug's risks.

Even when taken at recommended doses, acetaminophen, the primary active ingredient in Tylenol, can cause major damage to the liver, potentially leading to liver failure and even death. In fact, acetaminophen is currently the leading cause of sudden liver failure in the U.S., as its toxic metabolites have been shown to kill liver cells. The drug is so toxic that as many as 80,000 people are rushed to the emergency room annually due to acetaminophen poisoning, and another 500-or-so end up dead from liver failure.

These are disturbing figures that might come as a surprise to most people, especially considering that millions of Americans pop Tylenol and acetaminophen-containing drugs on a regular basis. But with more than 85 personal injury lawsuits and counting filed against the company in federal court, McNeil is feeling the heat from a drug that has long been claimed as one of the safest painkiller drugs on the market, which it clearly is not.

"The warning will make it explicitly clear that the over-the-counter drug contains acetaminophen, a pain-relieving ingredient that's the nation's leading cause of sudden liver failure," writes Matthew Perrone for the AP. "The new cap is designed to grab the attention of people who don't read warnings that already appear in the fine print on the product's label, according to company executives."

The new label, which will bear the phrases "CONTAINS ACETAMINOPHEN" and "ALWAYS READ THE LABEL," is set to first appear on all bottles of Extra Strength Tylenol, which contains more than 50 percent more acetaminophen per dose than regular strength Tylenol. And in the coming months, all bottles of Tylenol, including regular strength Tylenol, will bear the new label.

NyQuil, Sudafed, Excedrin and many other common drugs also contain acetaminophen

Despite the new label, McNeil, which is owned by drug giant Johnson & Johnson (J&J), insists that Tylenol is safe when taken as directed. But what the company fails to admit is that many people are taking not only Tylenol but also other drugs that contain acetaminophen, which increases their dose of the chemical to levels that are much higher than they probably realize.

According to the AP, nearly one in four Americans, or about 78 million people, consume drug products that contain acetaminophen in a given week. Some 600 over-the-counter drug products, it turns out, contain acetaminophen. These products include other painkiller drugs like Excedrin, for instance, as well as NyQuil cold formula and Sudafed sinus pills.

Combining these and other acetaminophen-containing drugs is a major cause of acetaminophen overdose, say experts, hence the addition of the new labels. But some people who stay well within the maximum daily dose of acetaminophen, which is currently set at 4,000 milligrams (mg) per day, still fall ill or die, which suggests that perhaps any level of acetaminophen is toxic and should be avoided.

"It's still a little bit of a puzzle," says Dr. Anne Larson from the Swedish Medical Center in Seattle, Washington. "Is it a genetic predisposition? Are they claiming they took the right amount, but they really took more? It's difficult to know."

Source: NaturalNews

Tylenol Just Once A Month Raises A Child’s Asthma Risk 540%

by Sarah Couture Pope

The vast majority of babies are given Tylenol (acetaminophen) within the first six months of life. It is the go to medicine for modern parents whenever discomfort or fever strikes even very young children and its use is frequently encouraged by many pediatricians.

Image: goeshealth.com

Now, a major study of over 20,000 children suggests that giving this popular medicine even as infrequently as once per year could have a permanent, life-threatening health effect.

Researchers at the University of A Coruna in Spain asked the parents of 10,371 children ages 6-7 and 10,372 adolescents aged 13-14 whether their children had asthma and how often they had been given acetaminophen within the previous year and when they were babies.
The children in the younger age group who had received the medicine only once per year were at 70% greater risk for asthma while those receiving Tylenol once a month or more were shockingly 540% more likely to have asthma.

The study, published in the European Journal of Public Health, also found that children who had even a single dose of Tylenol before their first birthday had a 60% risk of developing asthma.

In the older age group of 13 and 14 year-olds, asthma was 40 percent more likely if they had taken acetaminophen within the previous 12 months. The young teenagers were 250% more at risk if they took it once a month.

The researchers speculated that Tylenol, called paracetamol in the UK, may reduce a potent antioxidant called glutathione in the lungs and blood, which results in damage to the lung tissue. Glutathione is produced by the body (it is a combination of three amino acids:  cysteine, glycine and glutamine) and is referred to as the “mother” of all antioxidants by Dr. Mark Hyman MD.
While Tylenol use is strongly associated with a significant increase in asthma and the effect is greater the more often the drug is taken, no causal link is yet established via randomized-controlled trials. Does this mean the results of this large study should be dismissed and parents should continue favoring use of the popular over the counter medication for fever and pain?
Not so fast.

It would certainly be the wise and cautious approach for parents to investigate alternatives to Tylenol while additional follow-up research is performed.

Asthma rates have been on the increase for decades at the same time Tylenol use became more widespread. The potential link cannot and should not be ignored.

Examination of 20,000 children establishing such a strong associative risk must be taken seriously and the dismissal of the research by some doctors is irresponsible given the seriousness and life altering outcome of an asthma diagnosis.

“All the asthma symptoms analysed increased significantly with paracetamol consumption,” the researchers wrote.
Sources: RealFarmacy & The Healthy Economist

Article sources:

Babies given Calpol just once a month ‘are five times as likely to develop asthma’

Glutathione: The Mother of All Antioxidants

It’s Too Soon to Blame Paracetemol for Rising Childhood Asthma Rates

Exposure to Paracetemol and Asthma Symptoms

The effects of early and late paracetamol exposure on asthma and atopy: a birth cohort

Prenatal and infant acetaminophen exposure, antioxidant gene polymorphisms, and childhood 

asthma

Acetaminophen use and the risk of asthma in children and adults: a systematic review and 

metaanalysis

Reduce Your Child’s Asthma Risk by 41%